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WHAT IS ALPHA-LACTALBUMIN?

Alpha-lactalbumin (also referred to as alpha-lac)  is the main protein fraction in human milk and the second most abundant fraction in bovine milk. By utilizing advanced filtration and processing technologies, our NutriPRO™ Alpha-lactalbumin products contain up to twice the amount of alpha-lactalbumin as a standard whey protein. Alpha-lactalbumin from bovine and human sources have similar amino acid profiles.

ALPHA-LAC AND FORMULA

The use of alpha-lactalbumin in infant formula enables a lowering of the overall protein of a formula, while still satisfying the infant’s amino acid requirements. This may help optimize growth, development and long term metabolic and general health.

ALPHA-LAC AND GASTROINTESTINAL AND IMMUNE FUNCTION

The infant gut is immature, and several factors influence its development, most notably the nutrients and bioactive compounds found in milk. Alpha-lactalbumin likely exerts some of its beneficial impact on gut development and immune health through the release of bioactive peptides in the small intestine which have been found to have antimicrobial and prebiotic benefits. Furthermore, a study in rhesus monkeys found a lower incidence of E. coli induced diarrhea in those fed an alpha-enriched formula vs standard formula.

ALPHA-LACTALBUMIN AND SLEEP-WAKE CYCLE

Sleep is critical for infant growth and development, particularly brain development (Layman et al, 2018). Serotonin and melatonin are known to be key regulators of sleep across the lifespan; however, serotonin cannot cross the blood-brain barrier, thus it must be synthesized within the brain. The amino acid tryptophan is a precursor for serotonin and an amino acid able to cross the blood-brain barrier, hence it plays an important role in serotonin production. Alpha-lactalbumin is richer in tryptophan, thus may support the sleep-wake cycle in infants. In fact, feeding a tryptophan-rich infant formula at night has been shown to enhance sleep efficiency and total sleep time.